WAGR syndrome is an extremely rare genetic condition that can affect both boys and girls. It is the direct result of (typically) non-inherited deletions of genetic material around chromosome 11p13. There are less than a few hundred cases of WAGR syndrome reported in worldwide medical literature.
Babies born with WAGR syndrome often have eye problems, are at high risk for developing certain types of cancer, and are at a high risk for various developmental delays. The term “WAGR” stands for the first letters of the most common features associated with the condition:
- (W)ilms’ Tumor: the most common form of kidney cancer in children.
- (A)niridia: some or complete absence of the colored part of the eye, called the iris.
- (G)enitourinary problems: such as genital or urinary problems, testicles that are not descended or hypospadias (abnormal location of the opening for urination).
- (R)ange of Developmental Delays.